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4-Quinolone-3-carboxylic acid

Technical Data

Chemical name:4-Quinolone-3-carboxylic acid
Formula:C10H7NO3
Molecular weight:189.2
CAS number:13721-01-2
SMILES:OC(=O)c1c[nH]c2ccccc2c1=O

Cat. No. BRC0628

BRC0628

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Antiviral    Anti-infective    Antibacterial   

Target:

Kinases    Other kinases    G-Protein-Coupled Receptors (GPCRs)    Glutamate receptor    Enzymes    Kinases    Dehydrogenase    Enzyme-Linked Receptors    Receptor protein serine/threonine kinases   

Description:

4-Quinolone-3-carboxylic acidis a novel HIV-1 integrase strand transfer inhibitor.

Targets:Lactate dehydrogenase, Malate dehydrogenase, Glutamate dehydrogenase 1, mitochondrial, Casein kinase II subunit alpha
References:
1. WO2015/189560, 2015, A1.; 
2. Antiviral Drugs. 2011; 197-205.; 
3. ChemMedChem. 2010; 5(7), 1053-1066.; 
4. J. Med. Chem, 2006; 49, 22, 6443 - 6450.;