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calcium (3R,5R)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyheptanoate

Technical Data

Chemical name:calcium (3R,5R)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyheptanoate
Formula:C44H58CaF2N6O12S2
Molecular weight:1005.2
CAS number:1347797-73-2
SMILES:[Ca++].CC(C)c1nc(nc(-c2ccc(F)cc2)c1CC[C@@H](O)C[C@@H](O)CC([O-])=O)N(C)S(C)(=O)=O.CC(C)c1nc(nc(-c2ccc(F)cc2)c1CC[C@@H](O)C[C@@H](O)CC([O-])=O)N(C)S(C)(=O)=O

Cat. No. BRC0434

BRC0434

Prices

1.0 mg $ 83.0
2.0 mg $ 86.0
5.0 mg $ 91.0
10.0 mg $ 119.0
20.0 mg $ 205.0
25.0 mg $ 225.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents    Antiviral    Anti-infective   

Target:

Kinases    Mitogen-activated protein kinase (MAPK)    Enzymes    Kinases    Reductases    Enzyme-Linked Receptors    Receptor protein serine/threonine kinases   

Description:

Is rosuvastatin enantiomer compound that inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, also has inhibitory activity against human recombinant p38 MAP kinase expressed in Escherichia coli using myelin basic protein (MBP).

Targets:3-hydroxy-3-methylglutaryl-coenzyme A reductase, Mitogen-activated protein kinase 14
References:
1. U.S. Pat. Appl. Publ. 2014; US 20140088126 A1 20140327.; 
2. US2008/21054, A1, 2008.;