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Glutathione

GSH; Isethion; L-Glutathione Reduced;

Technical Data

Chemical name:Glutathione
Formula:C10H17N3O6S
Molecular weight:307.3
CAS number:70-18-8
SMILES:N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

Cat. No. BRC0918

BRC0918

Prices

1.0 mg $ 57.0
2.0 mg $ 58.0
5.0 mg $ 62.0
10.0 mg $ 82.0
20.0 mg $ 98.0
25.0 mg $ 105.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

G-Protein-Coupled Receptors (GPCRs)    GABA receptors    Enzymes    Cytochrome P450 (CYP)    Reductases    Peroxidases   

Description:

Glutathione reduces reactive oxygen species formed during cellular metabolism. Regulates activity of the redox-sensitive transcription factor NF-κB. Glutathione participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase.

Targets:Glutathione reductase, mitochondrial; Glutathione synthetase; Glutathione S-transferase Mu 1; Glutathione S-transferase kappa 1; Glutathione S-transferase A3; Glutathione S-transferase Mu 3; Glutathione S-transferase A4; Glutathione S-transferase Mu 4; Glutathione S-transferase A5; Glutathione S-transferase P; Glutathione S-transferase omega-1; Glutathione peroxidase 1; Glutathione peroxidase 2; Glutathione S-transferase theta-1; Maleylacetoacetate isomerase; Epididymal secretory glutathione peroxidase; Glutathione peroxidase 3; Lactoylglutathione lyase; Leukotriene C4 synthase; Microsomal glutathione S-transferase 3; Hematopoietic prostaglandin D synthase; Thioredoxin domain-containing protein 12; Glutathione S-transferase A1; Glutathione S-transferase A2; Microsomal glutathione S-transferase 1; S-formylglutathione hydrolase; Gamma-glutamyltranspeptidase 1; Glutathione S-transferase Mu 2; Glutaredoxin-1; Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; Glutathione S-transferase Mu 5; Glutathione peroxidase 6; Hydroxyacylglutathione hydrolase, mitochondrial; Glutathione peroxidase; Probable glutathione peroxidase 8; Glutathione peroxidase 7; Microsomal glutathione S-transferase 2; Glutathione S-transferase omega-2; Glutaredoxin-2, mitochondrial; Aldose reductase; Matrix metalloproteinase-9; Cytochrome P450 3A4;
References:
1. Eur J Clin Pharmacol. 1992; 43(6), 667-9.; 2. Mol Cell Endocrinol. 2006; 250(1-2), 70-9.; 3. Mol Cell Biochem. 1999; 196(1-2), 31-42.;