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Neramexane hydrochloride

Technical Data

Chemical name:Neramexane hydrochloride
Formula:C11H24ClN
Molecular weight:205.8
CAS number:209185-99-9
SMILES:Cl.CC1(C)CC(C)(C)CC(C)(N)C1

Cat. No. BRC1178

BRC1178

Prices

1.0 mg $ 83.0
2.0 mg $ 86.0
5.0 mg $ 91.0
10.0 mg $ 118.0
20.0 mg $ 186.0
25.0 mg $ 207.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

CNS Agents    Neurotransmitter Agents   

Target:

G-Protein-Coupled Receptors (GPCRs)    5-hydroxytryptamine receptor (5-HT receptor) inhibitors    Glutamate receptor    Ion Channels    Ligand-gated ion channels   

Description:

Neramexane hydrochloride is an NMDA antagonist with neuroprotective effects. It targets the cognitive decline in Alzheimer’s Disease by altering neurotransmitter signaling. Neramexane also acts as a nicotinic acetylcholine receptor antagonist.

Targets:Glutamate receptor ionotropic, NMDA 2D; 5-hydroxytryptamine receptor 3A; Nicotinic acetylcholine receptor;
References:
1. Curr. Top. Med. Chem. 2006; 6, 8, 749 - 770.; 2. Neuropharmacology. 1999; 38, 1, 85 - 108.; 3. Curr. Pharm. Des. 2002; 8, 10, 835 - 843.; 4.