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Gemcitabine

LY188011, NSC 613327, Zefei, DDFC

Technical Data

Chemical name:Gemcitabine
Formula:C9H11F2N3O4
Molecular weight:263.2
CAS number:95058-81-4
SMILES:Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1

Cat. No. BRC0771

BRC0771

Prices

1.0 mg $ 55.0
2.0 mg $ 56.0
5.0 mg $ 59.0
10.0 mg $ 78.0
20.0 mg $ 93.0
25.0 mg $ 100.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents    Antiviral    Anti-infective   

Target:

Kinases    Other kinases    Enzymes    Kinases    Reductases    DNA    SUBDNA   

Description:

Gemcitabine is an antineoplastic anti-metabolite that inhibits DNA synthesis.

Targets:DNA, Ribonucleoside-diphosphate reductase large subunit, Thymidylate synthase, UMP-CMP kinase
References:
1. Cancer Res. 2007; 67, 20, 9903.; 
2. Bioconjugate Chemistry. 2014; 25, 4, 813.; 
3. Drug Metab. Dispos. 2011; 39, 1, 132.;