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Cinoxacin

Compound 64716, NSC 304467, Noxigram, Uronorm

Technical Data

Chemical name:Cinoxacin
Formula:C12H10N2O5
Molecular weight:262.2
CAS number:28657-80-9
SMILES:CCn1nc(C(O)=O)c(=O)c2cc3OCOc3cc12

Cat. No. BRC0698

BRC0698

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 139.0
25.0 mg $ 151.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Anti-cancer agents    Anti-infective   

Target:

DNA    SUBDNA   

Description:

Cinoxacin is an antibacterial quinolone analog of oxolinic acid with in vitro activity against many gram-negative aerobic bacteria. It blocks DNA synthesis through inhibition of Topo II (DNA gyrase) as well as topoisomerase IV.

Targets:DNA gyrase subunit A, DNA
References:
1. J Agric Food Chem. 2006; 54, 8, 2822.; 
2. Antimicrob. Agents Chemother. 1996; 40, 8, 1835.; 
3. Antimicrob. Agents Chemother. 2000; 44, 12, 3322.;