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UK-371804

Technical Data

Chemical name:UK-371804
Formula:C14H16ClN5O4S
Molecular weight:385.8
CAS number:256477-09-5
SMILES:CC(C)(NS(=O)(=O)c1ccc2c(Cl)cnc(NC(N)=N)c2c1)C(O)=O

Cat. No. BRC0635

BRC0635

Prices

1.0 mg $ 118.0
2.0 mg $ 122.0
5.0 mg $ 132.0
10.0 mg $ 147.0
20.0 mg $ 263.0
25.0 mg $ 367.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Kinases    Other kinases    Proteases    Kinases    Proteases    Urokinase    Other proteases   

Description:

UK-371804 is a potent and selective inhibitor of urokinase-type plasmogen activator (uPA) (Ki=10 nM). Selectivity is 4000-fold versus tPA and 2700-fold versus plasmin.

Targets:Urokinase
References:
1. PCT Int. Appl. 2000; WO 2000005214 A2 20000203.; 
2. J. Phys. Chem. A. 2014; 118(39), 9113-9119.; 
3. U.S. 2000; US 6093731 A 20000725.;