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Zileuton

Zyflo, ICI D2138

Technical Data

Chemical name:Zileuton
Formula:C11H12N2O2S
Molecular weight:236.3
CAS number:111406-87-2
SMILES:CC(N(O)C(N)=O)c1cc2ccccc2s1

Cat. No. BRC0187

BRC0187

Prices

1.0 mg $ 82.0
2.0 mg $ 84.0
5.0 mg $ 89.0
10.0 mg $ 116.0
20.0 mg $ 140.0
25.0 mg $ 160.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Therapeutic areas:

Analgesics    Anti-Inflammatory   

Target:

Enzymes    Lipoxygenases   

Description:

Zileuton is an asthma drug that differs chemically and pharmacologically from other antiasthmatic agents. It blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.

Targets:Arachidonate 5-lipoxygenase
References:
1. Int J Clin Pract. 2007 Apr; 61(4):663-76.; 
2. Ann Pharmacother. 1996 Jul-Aug; 30(7-8):858-64. 3. Pulm Pharmacol. 1994 Apr; 7(2):73-9.;