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β-Nicotyrine

NSC 127943, NSC 407276

Technical Data

Chemical name:β-Nicotyrine
Formula:C10H10N2
Molecular weight:158.2
CAS number:487-19-4
SMILES:Cn1cccc1-c1cccnc1

Cat. No. BRC0582

BRC0582

Prices

1.0 mg $ 87.0
2.0 mg $ 89.0
5.0 mg $ 95.0
10.0 mg $ 122.0
20.0 mg $ 168.0
25.0 mg $ 189.0

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Biological activity

It belongs to next groups of Bioreference compounds:
Target:

Enzymes    Cytochrome P450 (CYP)    Ion Channels    Ligand-gated ion channels   

Description:

β-Nicotyrine is an alkaloid metabolite of nicotine. It binds CYP2A6 (IC50 = 2200nM), which is prominently involved in the metabolism of xenobiotics in the airways.

Targets:Nicotinic acetylcholine receptor, Cytochrome P450 2A6,
References:
1. Biochem. Pharmacol. 2004; 67(4), 751-756.; 
2. Drug Dev Res. 1998; 45, 1, 10 - 16.; 
3. US2010/298345, A1, 2010.;